Abstract: A new flue-cured tobacco varietiy Zhongyan 104 (systematically selected from Hongda at Nanjian), used Honghuadajinyuan as control, was analyzed and evaluated with regard to its economic attributes, leaf appearance quality, internal quality, and disease resistance. The results showed that, in the ecological conditions of Dali, leaf quality of Zhongyan104 was good, which could demonstrate characteristic high-quality tobacco in Dali "clear, sweet, fragrant, lubrication", With the development of Dali characteristic high-quality tobacco leaf production of Chinese style cigarette demand, industrial availability with higher; Important economic attributes in the annual performance relative stability, wide adaptability in the area. High yield, and resistance to tobacco black shank, angular leaf spot and blight and climate scab, fertilizer, easy to cure, The overall characters was better than those of Honghuadajinyuan, This variety can be used as a reserve for potential production in Dali, which has important industrial and agricultural values.