Abstract: The effects of different organic manures on growth, yield and quality of tobacco in purple soil field in Guangdong were investigated by field experiment. The results showed that the growth and development of tobacco plants were promoted by pig manure + peanut bran treatment, with earlier plant mature, and lower incidence of tobacco climate spot disease. In pig manure + peanut bran treatment, there were better maturity and more orange color in middle leaf, and more loose leaf structure and more moderate the identity of tobacco in upper leaf. There were higher contents of reducing sugar, total nitrogen, nicotine , protein and higher ratio of nitrogen /nicotine, higher sensory evaluation score of tobacco (B2F, C3F) in pig manure + peanut bran treatment.