Abstract: In order to investigate the characteristics of soil microelements in the central region of Guizhou Province. 165 soil profile samples were collected with GPS positioning and microelement contents of the soil samples were measured. The results showed that the soil samples were generally rich in available iron (Fe) and manganese (Mn), while available copper (Cu) and zinc (Zn) were insufficient. The available Fe content of soils developed from gully debris was higher than those developed from quaternary red clay and carbonate residual-slope wash. No significant difference of the contents of soil available Cu and available Zn was observed among soils originated from different parent materials. At the vertical direction of the soil profiles, the contents of microelement decreased with soil depth.