Abstract: In order to explore the prevention strategies of tobacco from being damaged by continuous low temperature stress, we clipped leaves damaged by low temperature stress to foster axillaries. The results showed that the growth period of the tobacco seedling that had been cut off leaf postponed than control treatment, the agronomic traits of the treatment was poorer than that of control, and the economic traits of the control was best in all treatment. Compared with the control, the differences of A treatment or B treatment, as the yield and yield value and high proportion of tobacco leaf and medium high proportion of tobacco leaf were significant or very significant. The economic traits of B treatment were slightly better than that of A treatment, but the differences were not significantly. In conclusion, it is inappropriate to take premature measures on tobacco seedlings damaged by frost, taking measures at time point after the damaged tobacco change into normal growth will be better.