Abstract: During the process of advancing modern tobacco agriculture, some related measures for developing were proposed, such as changing operation ideas, innovating production mode, strengthening the guidance, exploring lean production and so on. After a few year exploration, the lean production mode for flue-cured tobacco leaves has been roughly developed, which includes accurate information, sophisticated technology, precision operation, and fine management. The application of this mode increased land output rate, resource utilization rate and labor productivity, improved the quality and profit of flue-cured tobacco leaves, promoted the development of modern tobacco agriculture in Shandong. The strategy and issues on lean production for flue-cured tobacco leaves were evaluated and summarized in this paper.