Abstract: In order to study the differences of main chemical components and sensory styles of Yunyan 87 in different ecological regions of China, using simple descriptive statistics, variance analysis and correlation analysis, 288 Yunyan87 tobacco samples from four typical ecological regions of Southwest plateau, Guizhou mountain, Wulingqinba and Nanling hills were compared and analyzed.The results showed that in the Southwest plateau eco-zone the upper leaves were "high sugar and low nicotine", middle and lower leaves were "high sugar and middle nicotine".The characteristic flavor was sweet-smelling and the correlation coefficient with total sugar (0.679) was the largest.Irritation and gas mixture were small.In the ecological zone of Guizhou mountain, the upper leaves were "high nicotine and low potassium", and middle and lower leaves were "low nitrogen and high sugar".The characteristic flavor was positive and sweet and the correlation coefficient with total nitrogen (0.503) was the largest.The fragrance and aroma were high.In the Wulingqinba ecological zone, the upper leaves were "high nicotine and middle sugar", and the middle and lower leaves were "high sugar and high nicotine".The characteristic flavor of the fragrance was sweet and total nitrogen significant positive correlation coefficient (0.455) was the largest.Fragrance, aroma, concentration, strength and aftertaste were all small.In the Nanlin hills ecological zone, the upper leaves were "high potassium and nicotine and low sugar", and middle and lower leaves were "high potassium and low sugar".The characteristic flavor was caramelized and the correlation coefficient of reducing sugar (0.529) was the largest with high concentration and great strength.