Abstract: To analyse the effects of intercropping flue-cured tobacco with C. junce L. on controlling tobacco root-knot nematodes, a field experiment was carried out to study the effects of three different modes of intercropping tobacco with C. junce L. on root-knot nematode control efficiency, tobacco agronomic traits, yield, value of output and average price, using materials tobacco Yunyan 87 and C. junce L.I48. The results showed that, when the intercropping mode of tobacco to C. junce L. is 2 to 1, the agronomic traits of flue-cured tobacco were improved, with a nematode control efficacy of 41.67%, and the yield, value of output and average price of tobacco were increased by 456.69 kg/ha, 16 550.65 yuan/ha and 4.15 yuan/kg, respectively. When the intercropping mode of tobacco to C. junce L. is 1 to 1, the agronomic traits of flue-cured tobacco were improved significantly, with a nematode control efficacy of 53.53%, and the yield, value of output and average price of tobacco was increased by 843.85 kg/ha, 30295.42 yuan/ha and 6.39 yuan/kg, respectively. When the intercropping mode of tobacco to C. junce L. is 2 to 3, the plant height was reduced with a rate of 3.94% but no significant difference of the agronomic traits was observed compared with the no intercropping treatment. Tobacco yield was increased by 7.49 kg/ha, and the value of output and average price were reduced by 77.64 yuan/ha and 0.13 yuan/kg, respectively. These results indicated that 1 to 1 is the appropriate intercropping mode of tobacco to C. junce L. in controlling the damage caused by tobacco root-knot nematodes.