Abstract: A zero tillage experiment of flue-cured tobacco was carried out on the paddy soil and yellow soil from 2008 to 2009 in order to investigate the cultivation method of saving labor. The results showed that zero tillage had no significant effects on the growth of tobacco plant and the economic indices of cured leaves. In addition, zero tillage and zero tillage with straw mulch were able to improve the chemical components and the quality of sensory evaluation of cured leaves. In conclusion, zero tillage of flue-cured tobacco saved labor and cost obviously because of avoiding ploughing and ridging.