Abstract: Climatic tendency and accumulative anomaly percentage of temperature and precipitation were calculated by using the climate data from March to September (1961-2011) from climate station in Zunyi county, and response of the climate productivity to temperature and precipitation changes during the growth period of flue-cured tobacco was calculated by using the Thornth Waite Memorial model, so that the best transplanting time could be identified. The results showed that the temperature in middle September was generally lower than the best temperature for the growth of flue-cured tobacco, which was not favorable for the accumulation of dry matters and nutrient components during the maturation stage. The temperature from June to August and monthly precipitation were favorable to the growth of flue-cured tobacco. The precipitation increased from July to August but did not well distribute. Although the earliest day for flue-cured tobacco transplanting was April 10, the analysis of climate productivity showed that April 20 would be better than April 10. Therefore, we propose that the best starting date for tobacco transplanting in Zunyi county should April 20, but no later than May first.